Latest Article: Immunotherapy in Pancreatic Cancer

The Botta Laboratory
@ UCSD Moores Cancer Center

The Botta Laboratory @ UCSD Moores Cancer CenterThe Botta Laboratory @ UCSD Moores Cancer CenterThe Botta Laboratory @ UCSD Moores Cancer Center

The Botta Laboratory
@ UCSD Moores Cancer Center

The Botta Laboratory @ UCSD Moores Cancer CenterThe Botta Laboratory @ UCSD Moores Cancer CenterThe Botta Laboratory @ UCSD Moores Cancer Center
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  • More
    • Home
    • Dr. Botta Bio
    • Affiliations
    • News & Publications
    • Grants
    • UCSD Moores Cancer Center
    • Cend Therapeutics
    • Scripps Research
    • TumorGen MDx
  • Home
  • Dr. Botta Bio
  • Affiliations
  • News & Publications
  • Grants
  • UCSD Moores Cancer Center
  • Cend Therapeutics
  • Scripps Research
  • TumorGen MDx

Translational Oncology Research and Patient-Centered Care

Translational Oncology Research and Patient-Centered CareTranslational Oncology Research and Patient-Centered CareTranslational Oncology Research and Patient-Centered Care

A translational oncology & regenerative medicine laboratory dedicated to pancreatic cancer and solid tumors.

Contact Us

Division of Oncology, UCSD Moores Cancer Center

Translational Oncology Research and Patient-Centered Care

Translational Oncology Research and Patient-Centered CareTranslational Oncology Research and Patient-Centered CareTranslational Oncology Research and Patient-Centered Care

A translational oncology & regenerative medicine laboratory dedicated to pancreatic cancer and solid tumors.

Contact Us

Division of Oncology, UCSD Moores Cancer Center

About Us

Our Lab

The Botta Laboratory is broadly dedicated to understanding the mechanisms of Gastrointestinal Cancer growth and metastasis. Using pancreatic cancer as a model, we develop small proteins (peptides) to hijack tumor immune and metabolic processes for drug development.

Our Core Projects

Our current cancer-drug development programs achor on: 

     (1) Hijacking nutrient pathways for pancreatic cancer drugs 

     (2) Developing peptides that reverse Pancreatic cancer immune      suppression. 

     (3) Applying stem cell regenerative medicine technology to unlock cancer      growth programs.

Advanced Genomic Techniques

We implement the newest genetic techniques to map Pancreatic Cancer metabolism and immune cell regulatory pathways. Our single cell RNA sequencing (scRNA-seq) protocols are capable of characterizing single cells on an individual basis from patient tumor samples.

Support the Jeff Botta Gastrointestinal Research Fund

Support the Jeff Botta Gastrointestinal Research Fund

Your contribution will enable support for gastrointestinal research. and assist future patients on their journey. We are very grateful for your generosity.

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For Questions or Collaborations:

Botta Lab Core Projects:

Hijacking Nutrient Metabolism with Peptides

Reversing Cancer Immunosuppression via Peptides

Reversing Cancer Immunosuppression via Peptides

We use 3D in vitro and in vivo genetically engineered mouse models to target cancer with peptide delivery of therapeutics.

 

Reversing Cancer Immunosuppression via Peptides

Reversing Cancer Immunosuppression via Peptides

Reversing Cancer Immunosuppression via Peptides

We have unlocked novel peptides capable of destroying suppressive cells and thereby activating anti-tumor responses.

Single Cell RNA Sequencing

Reversing Cancer Immunosuppression via Peptides

Single Cell RNA Sequencing

Using sophisticated single cell sequencing techniques, we deconstruct patients' tumors, cell by cell, to uncover weaknesses to exploit.


Contact Us

Please send us a message for scientific questions or collaborations:

Botta Lab @ UCSD Moores Cancer Center

3855 Health Sciences Drive, La Jolla, California 92037, United States

NEW PATIENT REFERRAL @ UCSD Moores Cancer Center: 858.822.3115

Hours

Monday - Friday: 7:00am - 6:00pm

Saturday - Sunday: 9:00am - 4:00pm

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